Table 1.

Cohort Summary: New Orleans Alcohol Use in HIV Study

	Female (N = 108)		Male (N = 251)		Total (N = 359)
Variable	Median or %	IQR	Median or %	IQR	Median or %	IQR	P  a
Demographic
Age (years)	50	14	51	15	51	15	.707
African American race, %	87		82		84		.357
MSM, %			51		36		.662
Body mass index (kg/m2)	29	10	25	7	26	7	<.001
HIV
Viral loadb (copies/mL)	0	59	0	39	0	45	.539
<20, %	67		70		69		.759
20–200, %	13		16		15		.653
200–1 000 000, %	20		14		16		.281
ART adherence > 90%, %	81		86		84		.400
Hepatitis C coinfection, %	20		16		17		.386
Recent antibiotic usec, %	37		22		26		.004
Alcohol Use
AUDIT (score)	4	11	7	11	6	11	.004
Lifetime (g)	62 179	291 802	213 955	470 016	174 298	435 826	<.001
30-day (g)	84	399	224	915	168	754	.004
PEthd (ng/μL, N = 352)	14	89	49	240	34	179	<.001
Smoke-Tobacco Use
Current, %	52		64		60		.038
Pack-years in ever smokers	7	18	9	20	8	20	.039
Other Substance Use
30-day (days)	0	9	0	6	0	6	.662
Lifetime (years)	16	33	16	27	16	31	.557
CD8+ T Cells (cells/μL, N = 335)
Total	683	404	759	422	730	429	.115
Naive	157	128	139	127	144	129	.752
Activated	28	22	27	34	28	30	.890
Activated-senescent	13	17	13	21	13	20	.508
Exhausted	4	8	3	8	3	8	.441
TEMRA	71	63	62	69	64	65	.954
CD4+ T cells (cells/μL)
Total	548	378	484	340	505	365	.456
Naive	161	165	152	180	156	178	.635
Activated	9	7	9	7	9	7	.410
Effector memory	217	154	191	132	199	142	.187
TEMRA	1	4	1	4	1	4	.996
Gut Injury/Leak
iFABP (pg/mL)	688	916	876	790	841	819	.062
A1AT (fecal/plasma, N = 261)	1.4 × 10−6	1.7 × 10−6	1.3 × 10−6	1.5 × 10−6	1.3 × 10−6	1.5 × 10−6	.362
sCD14 (ng/mL)	3553	2996	3432	2931	3467	2967	.476

Abbreviations: A1AT, α-1-antitrypsin; ART, antiretroviral therapy; AUDIT, Alcohol Use Disorder Identification Test; iFABP, intestinal fatty acid-binding protein; HIV, human immunodeficiency virus; IQR, interquartile range; MSM, men who have sex with men; PEth, phosphatidylethanol; sCD14, soluble CD14; TEMRA, terminal effector memory cell re-expressing CD45RA.

^aWilcoxon signed-rank or χ ² test P values where variables were tested for association with sex. Bold indicates P < .050.

^bValues beneath the limit of detection (<20 copies/mL) were set to zero.

^cUsed in the preceding 4 months.

^dValues beneath the limit of detection (<8 ng/μL) were set to zero.