Table 1.
Country | Number of Ovale Cases/Study Sample | Prevalence, % | Symptomatic/ Asymptomatic | Mixed Infection or Monoclonal | Detection Method | Study Type | Study Yeara | Population | Ref. |
---|---|---|---|---|---|---|---|---|---|
Central Africa | |||||||||
Democratic Republic of Congo | 153/17 765 | 0.8 | Asymptomatic | Mixed | PCR | CS surveyb | 2013–2014 | Adults, 15+ y | This study |
Angola | 23/3316 | 0.2 | Asymptomatic | Mixed | PCR | CS surveyb | 2010 | All ages | [26] |
Cameroon | 31/742 | 4.2 | Asymptomatic | Monoclonal | Immunofluorescence | Surveyb | 1983 | All ages | [27] |
Central African Republic | 1/437 | 0.2 | Symptomatic | Monoclonal | Microscopy, PCR | Clinical | 2011 | Febrile patients, all ages | [28] |
Gabon | 4/206 | 1.9 | Symptomatic | Mixed | PCR | Clinical | 2005 | All ages | [29] |
Republic of Congo | 11/851 | 1.3 | Symptomatic | Mixed | PCR | Clinical, passive case detection | 2005 | All ages | [29] |
East Africa | |||||||||
Tanzania | 21/511 | 4.1 | Asymptomatic | Mixed | PCR | CS surveyb | 2016 | All ages | [30] |
Zambia | 18/873 | 2.1 | Asymptomatic | Mixed | PCR | CS surveyb | 2012 | All ages | [31] |
Malawi | 138/2873 | 4.8 | Asymptomatic | Mixed | PCR | CS surveyb | 2002 | All ages | [32] |
Southern Sudan | 1/392 | 0.3 | Symptomatic | Mixed | Microscopy | CS surveyb | 1975 | All ages | [33] |
Uganda | 36/2108 | 1.7 | Asymptomatic | Mixed | PCR | Clinical, CS survey | 2009 | All ages | [7] |
Kenya | 35/722 | 4.8 | Symptomatic | Mixed | PCR | Clinical, active case detection | 1998 | All ages | [29] |
West Africa | |||||||||
Ghana | 4/270 | 1.5 | Asymptomatic | Monoclonal | PCR | Longitudinalb | 2010 | Children 5–17 years | [34] |
Nigeria | 126/5211 | 2.4 | Asymptomatic | Mixed | Microscopy | CS surveyb | 2010 | Children < 5 years | [35] |
Liberia | 19/434 | 4.4 | Asymptomatic | Mixed | Microscopy | CS surveyb | 1957 | All ages | [36] |
Senegalc | 719/29 280 | 2.5 | Asymptomatic | Mixed | Microscopy | CS survey, longitudinalb | 1990–2010 | All ages | [37] |
Abbreviations: CS, cross-sectional, PCR, polymerase-chain reaction.
aYear(s) of sample collection.
bStudy is representative of the sampled population (ie, symptomatic based sampling methods were not employed).
cLongitudinal cross-sectional sampling of 1 study site across 20 years.