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. 2020 Aug 7;223(6):1005–1014. doi: 10.1093/infdis/jiaa478

Table 1.

Recent Prevalence Estimates for Plasmodium ovale Among sub-Saharan African Countries Based on Previously Published Studies

Country Number of Ovale Cases/Study Sample Prevalence, % Symptomatic/ Asymptomatic Mixed Infection or Monoclonal Detection Method Study Type Study Yeara Population Ref.
Central Africa
Democratic Republic of Congo 153/17 765 0.8 Asymptomatic Mixed PCR CS surveyb 2013–2014 Adults, 15+ y This study
Angola 23/3316 0.2 Asymptomatic Mixed PCR CS surveyb 2010 All ages [26]
Cameroon 31/742 4.2 Asymptomatic Monoclonal Immunofluorescence Surveyb 1983 All ages [27]
Central African Republic 1/437 0.2 Symptomatic Monoclonal Microscopy, PCR Clinical 2011 Febrile patients, all ages [28]
Gabon 4/206 1.9 Symptomatic Mixed PCR Clinical 2005 All ages [29]
Republic of Congo 11/851 1.3 Symptomatic Mixed PCR Clinical, passive case detection 2005 All ages [29]
East Africa
Tanzania 21/511 4.1 Asymptomatic Mixed PCR CS surveyb 2016 All ages [30]
Zambia 18/873 2.1 Asymptomatic Mixed PCR CS surveyb 2012 All ages [31]
Malawi 138/2873 4.8 Asymptomatic Mixed PCR CS surveyb 2002 All ages [32]
Southern Sudan 1/392 0.3 Symptomatic Mixed Microscopy CS surveyb 1975 All ages [33]
Uganda 36/2108 1.7 Asymptomatic Mixed PCR Clinical, CS survey 2009 All ages [7]
Kenya 35/722 4.8 Symptomatic Mixed PCR Clinical, active case detection 1998 All ages [29]
West Africa
Ghana 4/270 1.5 Asymptomatic Monoclonal PCR Longitudinalb 2010 Children 5–17 years [34]
Nigeria 126/5211 2.4 Asymptomatic Mixed Microscopy CS surveyb 2010 Children < 5 years [35]
Liberia 19/434 4.4 Asymptomatic Mixed Microscopy CS surveyb 1957 All ages [36]
Senegalc 719/29 280 2.5 Asymptomatic Mixed Microscopy CS survey, longitudinalb 1990–2010 All ages [37]

Abbreviations: CS, cross-sectional, PCR, polymerase-chain reaction.

aYear(s) of sample collection.

bStudy is representative of the sampled population (ie, symptomatic based sampling methods were not employed).

cLongitudinal cross-sectional sampling of 1 study site across 20 years.