Table 4.

Treatment of hypothyroidism with levothyroxine—cardiac concerns and effects on these risk factors.

Concerns	Effects
Cardiac insufficiency	Normalizes cardiac output
Ischemia and angina pectoris	Normalizes left ventricular contractile performance
Tachyarrhythmias	Lowers diastolic blood pressure
Pericardial effusion	Decreases serum cholesterol
High output failure without preexisting heart disease	Normalizes diastolic dysfunction
	Normalizes endothelial dysfunction