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. 2021 Mar 15;11:635667. doi: 10.3389/fonc.2021.635667

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Copyright © 2021 Lai, Chen, Fang and Chen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Flowchart of the study design. EORTC, European Organization for Research and Treatment of Cancer; QLQ, quality of life questionnaire; H&N, head and neck; EQ-5D, EuroQol- 5 Dimension; QoL, quality of life.