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. Author manuscript; available in PMC: 2021 Oct 28.
Published in final edited form as: Chem Rev. 2020 Sep 24;120(20):11479–11615. doi: 10.1021/acs.chemrev.0c00523

Figure 204.

Figure 204.

The general strategy for the peptide-catalyzed bromolactonization of pentenoic acid 10.40 to bromolactone 10.41 takes advantage of a bromoiodinane generated in situ to transfer bromenium ion to the olefin.454