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. Author manuscript; available in PMC: 2021 Oct 28.
Published in final edited form as: Chem Rev. 2020 Sep 24;120(20):11479–11615. doi: 10.1021/acs.chemrev.0c00523

Figure 217.

Figure 217.

(a) Henry reaction of benzaldehyde 11.58 with nitromethane 11.59 used to study the application of peptides derived from the Crt-1 Mets7 motif. (b) The unmodified structure of Crt-1 Mets7 (11.61a) that naturally binds Cu and modified scaffold 11.61b, which is more conformationally rigid.486