Table 4.
Recommended examinations for primary staging
| Test | Patients |
|---|---|
| Physical examination | All patients |
| Ultrasonography of the testes | All patients |
| Serum tumour markers | All patients |
| AFP | |
| β-hCG | |
| LDH | |
| Chest/abdominal/pelvic CT | All patients |
| Cranial MRI | Symptomatic patients and patients in the IGCCCG poor prognosis group, or patients with multiple pulmonary metastases and/or high β-hCG values (>5,000 IU/L) |
| Further diagnostics | Patients with unfinished family planning, active or postponed desire for offspring as well as for ruling out/detecting hypogonadism |
| Fertility tests | |
| Sperm analysis/cryopreservation | |
| Testosterone | |
| LH | |
| FSH | |
AFP, α-fetoprotein; hCG, human chorionic gonadotropin; LDH, lactate dehydrogenase; CT, computed tomography; IGCCCG, International Germ Cell Cancer Collaboration Group; LH, luteinizing hormone; FSH, follicle-stimulating hormone. We recommend advising all patients on the cryopreservation of sperm preferably before the primary surgical intervention and, if necessary, arrange consultation with an andrologist or a fertility centre.