Table 3.

Linear regression models for birth weight, head circumference, and birth length outcomes predicted by cannabis exposure during pregnancy

	Curtailed use versus previous use of cannabis, but not used during pregnancya			Prolonged use versus previous use of cannabis, but not used during pregnancyb
	B	95% CI	p value	B	95% CI	p value
Birth weight Cannabis in pregnancy − unadjustedc	−57	−166 to 53	0.31	−334	−507 to −160	<0.001
Cannabis in pregnancy − adjustedd	12	−88 to 112	0.82	−228	−354 to −102	<0.001
Birth length
Cannabis in pregnancy − unadjustedc	−0.5	−0.9 to 0.0	0.07	−1.0	−1.8 to −0.2	0.01
Cannabis in pregnancy − adjustedd	−0.1	−0.7 to 0.5	0.75	−0.5	−1.6 to 0.6	0.41
Head circumference
Cannabis in pregnancy − unadjustedc	−0.1	−0.4 to 0.3	0.74	−0.6	−1.2 to −0.1	0.03
Cannabis in pregnancy − adjustedd	0.2	−0.2 to 0.5	0.30	−0.4	−0.8 to 0.1	0.07

^aN = 4,981 for birth weight; N = 4,797 for birth length; N = 4,895 for head circumference.

^bN = 4,922 for birth weight; N = 4,736 for birth length; N = 4,838 for head circumference.

^cThe crude regression analyses were restricted to the same study sample as in the adjusted analysis.

^dAdjusted for a set of confounders: maternal age, education, parity, alcohol use during pregnancy (never, sometimes, and regular/binge), presence of symptoms of anxiety/depression, tobacco smoking in pregnancy (never, sometimes, and daily), use of illicit drugs, use of prescribed medications during pregnancy (opioids and benzodiazepines), work situation, planned pregnancy, and sex.