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. Author manuscript; available in PMC: 2021 Mar 29.
Published in final edited form as: Arch Pathol Lab Med. 2016 Feb;140(2):134–139. doi: 10.5858/arpa.2014-0612-OA

Table 2.

Disease Characteristics

Total Pediatric Adult P Value
Total cases 84 14 70
Tumor diameter, cm
 Mean (standard deviation) 2.2 (1.8) 2.3 (2.0) 2.2 (1.8) .82
 Median (interquartile range) 1.7 (1.0–2.8) 1.9 (1.0–2.9) 1.7 (1.0–2.5)
Multifocal, No. (%) 41 (49) 7 (50) 34 (49)
Extrathyroidal extension, No. (%) 14 (17) 3 (21) 11 (16) .69
Lymphatic/vascular invasion, No. (%) 7 (8.3) 4 (29) 3 (4.3) .01
Positive lymph nodes, No. (%) 28 (33) 9 (64) 19 (27) .01
Distant metastases, No. (%) 3 (3.6) 0 (0) 3 (4.3) >.99
Follow-up period, mo
 Mean (standard deviation) 31 (18) 32 (19) 31 (18) .78
 Median (interquartile range) 26 (19–43) 32 (16–44) 26 (20–41)
Positive for BRAF V600E, No. (%) 47 (61)a 4 (31) 43 (67) .03
a

Percents shown among 77 tumors (13 pediatric and 64 adult patient tumors) with an interpretable result.