Table 2.
Univariate and multivariate Cox analysis for the prediction of all‐cause death in patients with ADHF
| Unadjusted | Adjusted model a | |||
|---|---|---|---|---|
| HR (95% CI) | P‐value | HR (95% CI) | P‐value | |
| Overall cohort | ||||
| MELD‐XI score | 1.0827 (1.0553–1.1090) | <0.0001 | 1.0725 (1.0319–1.1137) | 0.0003 |
| FIB‐4 index | 1.3249 (1.2273–1.4218) | <0.0001 | 1.2173 (1.1077–1.3278) | <0.0001 |
| Patients with HFrEF | ||||
| MELD‐XI score | 1.1243 (1.0739–1.1721) | <0.0001 | 1.0876 (1.0130–1.1646) | 0.0179 |
| FIB‐4 index | 1.2765 (1.2680–1.4242) | <0.0001 | 1.2095 (1.0126–1.4165) | 0.0248 |
| Patients with HFmrEF | ||||
| MELD‐XI score | 1.1661 (1.0961–1.2358) | <0.0001 | 1.2101 (1.1137–1.3156) | <0.0001 |
| FIB‐4 index | 1.4184 (1.1736–1.6793) | 0.0001 | 1.2685 (0.9941–1.5867) | 0.0441 |
| Patients with HFpEF | ||||
| MELD‐XI score | 1.1350 (1.0956–1.1730) | <0.0001 | 1.0435 (0.9765–1.1151) | 0.2085 |
| FIB‐4 index | 1.3618 (1.2020–1.5204) | <0.0001 | 1.3454 (1.1521–1.5473) | <0.0001 |
ADHF, acute decompensated heart failure; CI, confidence interval; FIB‐4, fibrosis‐4; HFmrEF, heart failure with mid‐range ejection fraction; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; HR, hazard ratio; MELD‐XI, model for end‐stage liver disease excluding international normalized ratio.
a
Adjusted for age, sex, left ventricular ejection fraction, haemoglobin level, serum sodium level, serum chloride level, serum uric acid level, and plasma brain natriuretic peptide level at discharge.