Table 4.
Univariate and multivariate Cox analysis for the prediction of non‐cardiac death in patients with ADHF
| Unadjusted | Adjusted model a | |||
|---|---|---|---|---|
| HR (95% CI) | P‐value | HR (95% CI) | P‐value | |
| Overall cohort | ||||
| MELD‐XI score | 1.0656 (1.0269–1.1017) | 0.0004 | 1.0496 (0.9941–1.1065) | 0.0753 |
| FIB‐4 index | 1.3268 (1.1942–1.4583) | <0.0001 | 1.2401 (1.0959–1.4032) | 0.0006 |
| Patients with HFrEF | ||||
| MELD‐XI score | 1.1018 (1.0246–1.1716) | 0.0041 | 1.0375 (0.9318–1.1511) | 0.4926 |
| FIB‐4 index | 1.2867 (1.0650–1.5074) | 0.0040 | 1.2716 (0.9820–1.5922) | 0.0463 |
| Patients with HFmrEF | ||||
| MELD‐XI score | 1.1742 (1.0836–1.2644) | <0.0001 | 1.2706 (1.1338–1.4309) | <0.0001 |
| FIB‐4 index | 1.4867 (1.1768–1.8295) | 0.0004 | 1.3938 (1.0201–1.8648) | 0.0285 |
| Patients with HFpEF | ||||
| MELD‐XI score | 1.0211 (0.9577–1.0773) | 0.4828 | 1.0252 (0.9336–1.1207) | 0.5900 |
| FIB‐4 index | 1.3312 (1.1151–1.5439) | 0.0005 | 1.3324 (1.0708–1.6107) | 0.0052 |
ADHF, acute decompensated heart failure; CI, confidence interval; FIB‐4, fibrosis‐4; HFmrEF, heart failure with mid‐range ejection fraction; HFpEF, heart failure with preserved ejection fraction; HFrEF, heart failure with reduced ejection fraction; HR, hazard ratio; MELD‐XI, model for end‐stage liver disease excluding international normalized ratio.
a
Adjusted for age, sex, left ventricular ejection fraction, haemoglobin level, serum sodium level, serum chloride level, serum uric acid level, and plasma brain natriuretic peptide level at discharge.