Figure 1.

Response of cardiac index (CI, Panel A), pulmonary artery wedge pressure (PAWP, Panel B), indexed pulmonary vascular resistances (PVRi, Panel C), right ventricular end‐diastolic pressure (RVEDP, Panel D), left ventricular stroke work index (LVSWi, Panel E), and right ventricular stroke work index (RVSWi, Panel F) to vasodilator challenge with levosimendan (n = 14), NO (n = 14), and iloprost (n = 7) in end‐stage heart failure patients. Stable baseline and post‐drug infusion data are represented (before and after, respectively). Group means and standard deviations are represented in Panels A–E whereas box plots are represented in Panel F, according to test assumptions. Individual patient values are depicted as point plots with connecting thin lines while thick lines represent changes in means for Panels A–E and relative treatment effect in the insert to Panel F. P values for main effects of drug (D) and time (T) and interaction (D*T) are represented in each panel. *P < 0.05 levosimendan vs other groups' response over time.