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. 2021 Jan 5;8(2):1156–1166. doi: 10.1002/ehf2.13161

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© 2021 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Preload recruitable stroke work (SW) (PRSW) as SBM_w in patients with nonischemic dilated cardiomyopathy. Comparison of SBM_w and SW/EDV before (A) and after adding mineralocorticoid receptor antagonist (MRA) (B). Comparison of SBM_w and SW/EDV adjusted for peripheral vascular elastance (Ea) (TCP) before (C) and after adding MRA (D). PRSW increased markedly after adding MRA (Panel A vs. B). Increased slope of the [(SW/EDV)/Ea]‐SBM_w relation after MRA demonstrated both increase in PRSW and sensitivity to Ea (Panel B vs. D). Please refer to the text for details. EDV, end diastolic volume; SBM, single‐beat method.