Table 2.
Baseline parameters of LV performance and ventriculo–arterial coupling
| NIDCM N = 12 | Normal N = 11 | P | |
|---|---|---|---|
| LVEF (%) | 24 (17, 27) | 66 (62, 67) | <0.001 |
| LVEDVI (mL/m2) | 82 (74, 91) | 63 (55, 75) | 0.002 |
| LVESVI (mL/m2) | 63 (56, 78) | 19 (17, 28) | <0.001 |
| LVSVI (mL/m2) | 19 (14, 21) | 41 (37, 47) | <0.001 |
| LV mass (g) | 169 (154, 203) | 69 (49, 77) | <0.001 |
| TVR (Wood units) | 2.69 (2.23, 3.85) | 1.48 (1.38, 1.75) | <0.001 |
| Ea | 2.89 (2.34, 4.00) | 1.53 (1.34, 1.67) | <0.001 |
| Ees (sb) | 0.96 (0.75, 1.43) | 1.44 (1.26, 1.64) | 0.016 |
| Ea/Ees (sb) | 3.08 (2.54, 3.78) | 0.95 (0.91, 1.11) | <0.001 |
| Pes/Ves | 0.83 (0.65, 0.95) | 3.04 (2.63, 3.49) | <0.001 |
| V0 | 16 (−14, 38) | −38 (−39, −24) | 0.001 |
| ESV‐100 | 121 (104, 148) | 30 (27, 37) | <0.001 |
| SBMw | 35 (24, 45) | 113 (101, 119) | <0.001 |
| TCP | 7.4 (3.4, 11.4) | 40.2 (35.2, 43.8) | <0.001 |
| Ea/[Pes/Ves] | 3.24 (2.65, 4.83) | 0.51 (0.49, 0.60) | <0.001 |
| Vw | 71.3 (60.2, 90.2) | 51.1 (49.2, 56.4) | 0.012 |
Median (interquartile range). Pairwise comparisons between groups using Wilcoxon rank sum test, with Bonferroni corrected threshold P < 0.0166 for significance. Ea, arterial elastance (mmHg/mL); Ea/[Pes/Ves], arterial elastance/end‐systolic pressure/end‐systolic volume ratio; Ees (sb), end‐systolic elastance (single‐beat method) (mmHg/mL); ESV‐100, end‐systolic volume at 100 mmHg (mL); LV, left ventricular; LVEDVI, LV end‐diastolic volume index; LVEF, LV ejection fraction; LVESVI, LV end‐systolic volume index; LVSVI, LV stroke volume index; Pes/Ves, end‐systolic pressure/end‐systolic volume ratio; SBMw, slope of preload recruitable stroke work relation (single‐beat method) (erg.cm−3 103); TCP, total circulatory performance (stroke work/end‐diastolic volume/Ea); TVR, total vascular resistance; V0, end‐systolic volume at SBP 0 mmHg (mL); Vw, LV volume at Stroke Work 0.