Table 1.
Inclusion criteria |
(1) Symptomatic paroxysmal or persistent AF (paroxysmal: ≥2 symptomatic or one documented AF episode lasting 30 s or more in the last 3 months; persistent: ≥1 documented episode in the last 3 months) |
(2) Eligible for heart transplantation due to end‐stage heart failure |
(3) LV dysfunction with left ventricular ejection fraction ≤35% (measured in the last 6 weeks prior to enrolment) |
(4) NYHA class ≥II |
(5) Indication for ICD therapy due to primary prevention |
(6) Dual‐chamber ICD with home monitoring capabilities already implanted |
(7) The patient is willing and able to comply with the protocol and has provided written informed consent |
(8) Sufficient GPRS network coverage in the patient's area |
(9) Age ≥18 years |
Exclusion criteria |
(1) Documented left atrial diameter >6 cm (parasternal long‐axis view) |
(2) Contraindication for chronic anticoagulation therapy or heparin |
(3) Previous left heart ablation procedure for atrial fibrillation |
(4) Acute coronary syndrome, cardiac surgery, angioplasty, or cerebrovascular accident within 2 months prior to enrolment |
(5) Untreated hypothyroidism or hyperthyroidism |
(6) Enrolment in another investigational drug or device study |
(7) Woman currently pregnant, breastfeeding, or not using reliable contraceptive measures during fertility age |
(8) Mental or physical inability to participate in the study |
(9) Listed as ‘high urgent’ for heart transplantation |
(10) Cardiac assist device implanted |
(11) Planned cardiovascular intervention |
(12) Life expectancy ≤12 months |
(13) Uncontrolled hypertension |
(14) Requirement for dialysis due to end‐stage renal failure |
AF, atrial fibrillation; GPRS, General Packet Radio Service; ICD, implantable cardioverter defibrillator; LV, left ventricular; NYHA, New York Heart Association.