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mRNA expression of genes evaluated in cardiac biopsies in controls (CTR), chronic heart failure patients with preserved ejection fraction (HFpEF) or reduced ejection fraction (HFrEF): (A) IGF‐1 circulating levels; (B) IGF‐1 mRNA; (C) IGF‐1R mRNA; (D) GHR mRNA; (E) SERCA2 mRNA; (F) GRK5 mRNA; (G) GRK2 mRNA; (H) ADRB1 mRNA; (I) ADRB2 mRNA; and (J) TNF‐α mRNA. *P < 0.05.
