Survival analysis of individuals with sporadic mesothelioma or familial mesothelioma by BAP1 mutation status. Kaplan–Meier survival probability versus years with number at risk. Survival data combine results from references: (54, 67, 99). Blue, familial BAP1WT mesothelioma (median survival, 8 years; 10-year survival, 42.0%); red: familial BAP1+/− mesothelioma (median survival, 5 years; 10-year survival, 14.1%); green: SEER, stage I (median survival, 11 months; 10-year survival, 9.2%); brown: SEER, all stages (median survival, 8 months; 10-year survival, 3.3%). Rows below the graph indicate the number of patients at risk in each cohort per year. BAP1+/−, heterozygous BAP1-inactivating mutations; BAP1WT, wild-type BAP1; MM, malignant mesothelioma.