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BOLD activity during hand movements in healthy controls and patients (FWE corrected; p < 0.05 at the cluster level). Compared with (A) controls, (B) patients had enhanced activity in ipsilesional and contralesional motor areas when moving their affected hand. (C) The overactivity was reduced after administration of RBX compared with PBO. BOLD = blood oxygen level dependent; FWE = family-wise error; PBO = placebo; RBX = reboxetine.
