Whole-brain voxelwise analysis. RBX effects during movements of the affected hand (FWE corrected; p < 0.05). Compared with PBO, RBX significantly reduced the BOLD activity in both hemispheres, including (a) ipsilesional middle frontal gyrus, (b) bilateral anterior cingulate cortex, (c) ipsilesional inferior frontal gyrus (ventral premotor cortex), (d) ipsilesional temporoparietal junction/superior temporal gyrus, (e) contralesional superior frontal gyrus, (f) ipsilesional middle cingulate cortex, (g) ipsilesional superior medial frontal gyrus, and (h) contralesional superior medial frontal gyrus. BOLD = blood oxygen level dependent; FWE = family-wise error; PBO = placebo; RBX = reboxetine.