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. 2021 Mar 26;9(1):e001927. doi: 10.1136/bmjdrc-2020-001927

Table 4.

Factors associated with diabetes incidence by ethnicity, Cox proportional hazards analysis

Variables South Asians US blacks US whites
HR (95% CI) HR (95% CI) HR (95% CI)
Age 0.98 (0.82 to 1.18) 1.05 (0.77 to 1.43) 1.03 (0.82 to 1.30)
Age square 1.00 (1.00 to 1.00) 1.00 (1.00 to 1.00) 1.00 (1.00 to 1.00)
Sex (men) 0.89 (0.66 to 1.19) 1.00 (0.83 to 1.20) 0.98 (0.86 to 1.11)
BMI (per unit) 1.05 (1.02 to 1.08) 1.04 (1.02 to 1.05) 1.06 (1.04 to 1.07)
Family (parental) history of diabetes (yes) 1.23 (0.86 to 1.75) 1.37 (1.14 to 1.65) 1.53 (1.35 to 1.75)
Log HOMA-IR (per SD) 2.67 (2.05 to 3.48) 14.55 (11.11 to 19.07) 34.64 (27.63 to 43.42)
Log HOMA-B (per SD) 0.44 (0.34 to 0.58) 0.08 (0.06 to 0.11) 0.05 (0.04 to 0.06)

Diabetes defined as FPG ≥7.00 mmol/L (126 mg/dL) or HbA1c ≥48 mmol/mol (6.5%) or self-reported/physician-diagnosed diabetes or medication.

BMI, body mass index; FPG, fasting plasma glucose; HOMA-B, homeostasis model assessment of β-cell dysfunction; HOMA-IR, homeostatic model assessment of insulin resistance; HR, hazard ratio.