FIGURE 7-1.
Proportion of patients with human immunodeficiency virus (HIV) infection with HIV-associated neurocognitive disorder (HAND) in the pre–antiretroviral therapy (ART) era (A) and ART era (B). The overall portion of people with HIV infection with HAND has not substantially changed between the pre-ART era and the current ART era. However, there has been a shift toward milder HAND stages with asymptomatic neurocognitive impairment (ANI) being much more common and HIV-associated dementia (HAD) being much less common, while minor neurocognitive disorder (MND) has remained relatively stable today compared to the pre-ART era.
Modified with permission from Saylor D, et al, Nat Rev Neurol.9 © 2016 The Authors.