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. 2021 Mar 29;16(3):e0249266. doi: 10.1371/journal.pone.0249266

Table 6. Secretion of Myxobolus cerebralis serpin proteins predicted with models OutCyte, SectretomeP and SRTpred.

OutCyte Score (threshold = 0.5) SecretomeP 2.0 Score (threshold = 0.5) SRTpred Score (threshold = 0.0) Arginine content pI
Mc-S1 UPS 0.501 UPS 0.691 Non-Secretory -0.450 7 6.11
UPS (AA) 0.118
UPS (properties) 0.382
UPS (dipeptide) 0.208
Mc-S3 Intracellular 0.668 Intracellular 0.485 UPS (hybrid) 0.945 10 5.18
UPS (AA) 0.120
UPS (properties) 0.821
Non-Secretory(dipeptide) -0.034
Mc-S4 UPS 0.502 Intracellular 0.483 UPS (hybrid) 1.027 6 6.05
UPS (AA) 0.145
UPS (properties) 0.625
Non-Secretory(dipeptide) -0.610
Mc-S5 Intracellular 0.514 UPS/Intracellular 0.527 UPS (hybrid) 1.125 3 5.43
UPS (AA) 0.132
UPS (properties) 0.726
UPS (dipeptide) 0.790

pI: isoelectric point; UPS: unconventional protein secretion, i.e. secretory pathway that act without the involvement of an identified N-terminal signal peptide [70].