Skip to main content
. 2021 Mar 17;17(3):e1009447. doi: 10.1371/journal.ppat.1009447

Fig 5. Binding sites used by SZF1 to silence EBV lytic genes are not used to repress host genes during latency.

Fig 5

SZF1 was depleted using a validated siRNA or a control non-targeting siRNA (siScram) in HH514-16 BL cells. After 24 hours, NaB was added to activate EBV lytic cycle. After another 24 hours, cells were harvested for RNA extraction and RT-qPCR analysis of host genes harboring the BZLF1p binding site (A-C) or the BDLF2 binding site (D-I). Data represent averages of two independent experiments; error bars, SEM; *, p < 0.05; **, p < 0.01; ***, p < 0.001.