Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Apr 30;63(18):10170–10187. doi: 10.1021/acs.jmedchem.0c00415

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

DT network of all approved drugs (A) and of EMs (B). The DT network is generated by using the known associations between drugs and targets extracted from the DrugBank database.²¹ As of March 2, 2020, DrugBank (version 5.1.5, released 2020-01-03) includes 2635 approved small molecule drugs and 1367 approved biologics. Additionally, 1148 nonredundant proteins (that are drug target/enzyme/transporter/carrier) sequences are linked to these drug entries. Small and big circles correspond to drugs and target proteins, respectively. A link is placed between a drug node and a target node if the protein is a known target of that drug. Drug nodes and connecting links are colored according to the ATC 1st level code of the drug. A bigger representation of the DT network is present in the Supporting Information.