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| all
organic EMs (n = 345) |
||||
|---|---|---|---|---|
| all, n (%) | de novo, n (n = 143) | nature-inspired, n (n = 132) | natural, n (n = 70) | |
| achiral compounds | 126 (37a) | 84 | 29 | 13 |
| chiral compounds | 219 (63a) | 59 | 103 | 57 |
| 1 stereocenter | 50 (23b) | 28 | 15 | 7 |
| >1 stereocenter | 169 (77b) | 31 | 88 | 50 |
| mixture of stereoisomers | 18 (8b) | 11 | 5 | 2 |
| single stereoisomer | 201 (92b) | 48 | 98 | 55 |
% of compounds on a total of 345 active principles included in the EML.
% of compounds on a total of 219 chiral compounds.
