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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Hepatol. 2020 Jul 16;73(6):1470–1481. doi: 10.1016/j.jhep.2020.07.016

Figure 6. Pharmacological inhibition of IRAK4 attenuates ethanol-induced liver injury.

Figure 6.

C57BL/6J mice were allowed free access to ethanol or pair-fed control; during last week of feeding or certain time points, IRAK4/1 inhibitor were orally administered 10 mg/kg body weight twice/day (A, B). (C, D) Paraffin-embedded liver sections were stained with H&E. (E) AST and ALT activity was determined in plasma. (F) Hepatic triglyceride content was measured in whole-liver homogenates. Values represent means ± SEM, n=4-6 per group. *, p < 0.05 by Two-way ANOVA test.