Figure 1.
Current working model of the C53 receptor complex. Upon ribosome stalling/collisions, UFM1 is transferred from the C53 receptor complex (C53-UFL1-DDRGK1) to the tail of the ribosomal subunit RPL26. This exposes the sAIMs on C53 for ATG8/GABARAP binding and subsequent complex recruitment to the phagophore for degradation