Table 4.
Logistic regression models of mortality outcome
| Unadjusted Model | Adjusted Model I | Adjusted Model II | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Demographics | OR | 95% CI | P-value | aOR1 | 95% CI | P-value | aOR1 | 95% CI | P-value |
| Age > 65 | 2.790 | 1.914–4.065 | <0.001 | 2.277 | 1.481–3.501 | <0.001 | 2.295 | 1.492–3.529 | <0.001 |
| BMI | 0.986 | 0.962–1.012 | 0.293 | ||||||
| Male Sex | 1.311 | 0.920–1.870 | 0.134 | 1.535 | 1.029–2.288 | 0.036 | 1.557 | 1.044–2.323 | 0.030 |
| Comorbidities | |||||||||
| DM | 1.266 | 0.887–1.808 | 0.194 | 0.856 | 0.565–1.299 | 0.465 | 0.860 | 0.567–1.303 | 0.476 |
| HTN | 2.738 | 1.720–4.358 | <0.001 | 2.157 | 1.181–3.939 | 0.012 | 2.163 | 1.187–3.942 | 0.012 |
| HLD | 1.643 | 1.148–2.351 | 0.007 | 1.392 | 0.924–2.097 | 0.113 | 1.390 | 0.922–2.095 | 0.116 |
| Heart disease | 1.458 | 1.003–2.120 | 0.048 | 0.677 | 0.429–1.069 | 0.094 | 0.676 | 0.428–1.069 | 0.094 |
| Asthma | 1.156 | 0.715–1.868 | 0.554 | ||||||
| COPD | 1.338 | 0.778–2.302 | 0.292 | ||||||
| CKD | 1.889 | 1.309–2.725 | 0.001 | 1.257 | 0.801–1.974 | 0.320 | 1.234 | 0.784–1.942 | 0.364 |
| Cancer | 1.298 | 0.833–2.024 | 0.250 | ||||||
| Lab Findings | |||||||||
| Hemoglobin | 0.972 | 0.914–1.034 | 0.365 | ||||||
| Ferritin* | 1.000 | 1.000–1.000 | <0.001 | ||||||
| D-dimer* | 1.142 | 1.101–1.185 | <0.001 | ||||||
| WBC | 1.027 | 0.986–1.070 | 0.199 | ||||||
| CRP* | 1.080 | 1.058–1.103 | <0.001 | ||||||
| Platelet | 0.998 | 0.006–0.999 | 0.006 | 0.997 | 0.995–0.999 | 0.005 | 0.997 | 0.995–0.999 | 0.005 |
| ALT** | 1.001 | 1.000–1.003 | 0.095 | ||||||
| AST | 1.004 | 1.000–1.008 | 0.048 | 1.004 | 1.000–1.008 | 0.033 | 1.004 | 1.000–1.008 | 0.033 |
| Creatinine*** | 1.091 | 1.025–1.161 | 0.006 | ||||||
| Classifications | |||||||||
| Anemia (on admission) vs. none | 1.541 | 1.079–2.200 | 0.017 | 1.523 | 1.008–2.303 | 0.046 | |||
| Anemia Severity | |||||||||
| Mild vs. none | 1.496 | 0.913–2.451 | 0.011 | 1.406 | 0.823–2.404 | 0.212 | |||
| Mod-Sev vs. none | 1.587 | 1.118–2.253 | 0.010 | 1.671 | 1.090–2.563 | 0.019 | |||
Model I: Adjusted model for the association between anemia and all-cause mortality, Model II: Adjusted model for the association between different severities of anemia and all-cause mortality.1Adjusted Odds Ratio. *Variables with 20% or more missing values were not included in the multivariable model due to too many missing values. **ALT was not included in multivariable models because of the high correlation with AST which appeared to be the highest predictive variable in bivariate analysis. ***Creatinine was not included in multivariable models because of the high correlation with CKD which appeared to be the highest predictive variable in bivariate analysis.