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. 2021 Apr;27(4):1110–1122. doi: 10.3201/eid2704.203612

Table 2. Specific alleles of antigenic genes in 4 sublineages of clonal complex 4821 of Neisseria meningitidis.

Sublineage Antigen allele no. (no. isolates)
PorA fHbp nhba PorB FetA-VR opcA nspA tbpA NMB-0315
L44.1, n = 50 P1.7–2,14 (25) 22 (12) 124 (48) 3–48 (47) F3–3 (45) None 4 (49) 7 (36) None
P1.12–1,16–8 (9) 489 (13)


498 (15)







L44.2, n = 29 None None 965 (10) 3–81 (15) F1–91 (20) None None None 335 (26)



967 (12)






L44.3, n = 58 P1.17–6,23-x* (23) None None 3–229 (35) F3–9 (8) 100 (40) 26 (39) 1,333 (31) 194 (49)





F3–36 (37)




L44.4, n = 32 P1.5–3,10–2 (8) None None 3–460 (7) F1–7 (11) None 117 (20) None None

*23-x refers to 23, 23–2, and 23–6.