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. 2021 Mar 29;11:7118. doi: 10.1038/s41598-021-86482-x

Table 4.

Adverse event after bevacizumab/capecitabine treatment.

Adverse events Any grade Grade 3 or 4
Any event 157 (100%) 28 (17.8%)
Hand foot syndrome 92 (58.6%) 8 (5.1%)
Fatigue 24 (15.3%) 2 (1.3%)
Nausea 14 (8.9%) 4 (2.6%)
Vomiting 8 (5.1%) 3 (1.9%)
Mucositis 35 (22.3%) 2 (1.3%)
Diarrhoea 16 (10.2%) 1 (0.6%)
Neutropenia 39 (24.8%) 5 (3.2%)
Thrombocytopenia 54 (34.4%) 2 (1.3%)
Anaemia 96 (61.1%) 2 (1.3%)
LFT elevation 76 (48.4%) 2 (1.3%)
Bilirubin elevation 64 (40.8%) 5 (3.2%)
Proteinuria 10 (6.4%) 3 (1.9%)
Bleeding/haemorrhage 11 (7.0%) 2 (1.3%)
Gastrointestinal perforation 1 (0.6%) 1 (0.6%)
Thromboembolic event 0 (0.0%) 0 (0.0%)