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. 2021 Jan 19;124(7):1199–1206. doi: 10.1038/s41416-020-01220-w

Table 3.

HR with 95% CI for complete response in locally advanced basal cell carcinoma associated with patient and tumour characteristics (n = 44).

Characteristic HR with 95% CI univariable analysis P value HR with 95% CI multivariable analysis P value
Age (per year)a 0.99 (0.96–1.03) 0.85
Sex
  Male 1.00
  Female 1.78 (0.63–5.07) 0.28
Tumour size (per cm)b 0.91 (0.79–1.06) 0.24 0.77 (0.62–0.95) 0.02
Tumour location
  Not on the head 1.00 0.86
  On the head 0.90 (0.25–3.18)
Tumour subtype
  Non-infiltrative 1.00 0.16 1.00 0.06
  Infiltrative 0.46 (0.16–1.35) 0.21 (0.04–1.08)
Bone invasion
  No 1.00 0.67
  Yes 0.78 (0.25–2.46)
Previous therapy
  No 1.00 0.44 1.00 0.22
  Yes 0.44 (0.24–1.86) 0.46 (0.13–1.58)
Previous radiotherapy
  No 1.00 0.61
  Yes 1.40 (0.39–5.06)
Participant in trial
  No 1.00 0.09 1.00 <0.01
  Yes 2.38 (0.86–6.58) 10.08 (2.14–47.43)

HRs for complete response with 95% CI in patients with laBCC.

HR > 1 and HR < 1 indicate increased and decreased probability of response, respectively, where categories with HR = 1 were used as the reference category. P < 0.05 is considered statistically significant.

HRs hazard ratios, 95% CI 95% confidence interval.

aThe HR for age represents the increase in probability per year.

bThe HR for tumour size represents the increase in probability per cm.