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. 2021 Mar 25;14:1069–1084. doi: 10.2147/JIR.S296597

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© 2021 Liu et al.

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The expression and prognostic value of FUT7 in BLCA. (A) FUT7 expression in bladder cancer was analyzed by Oncomine database. 0: No value (n=48); 1: Superficial bladder cancer (n=28); 2: Infiltrating bladder urothelial carcinoma (n=81). (B) Immunohistochemical staining of FUT7 in bladder cancer tissues and normal bladder tissues. The representative images and statistical analysis were shown. (C) ELISA assay of FUT7 level in serum samples from patients with bladder cancer and healthy controls. (D) ROC curve analysis of the diagnostic value of FUT7 for bladder cancer. (E) Overall survival curve of FUT7 for probe 217696_at in bladder cancer cohort (GSE5287) and disease-specific survival curve of FUT7 for probe ILMN_1715286 in bladder cancer cohort (GSE13507) from PrognoScan database. (F) Analysis of the genetic alteration frequency of FUT7 in BLCA by cBioPortal, including missense mutation, amplification, deep deletion and mRNA high. (G) The overall survival curve and disease-free survival curve of FUT7 for BLCA in FUT7-altered and unaltered group. *P<0.05, ***P<0.001.