Table 2.

Summary of Cox proportional hazard regression of ALG5, GPR107, NUP188 in TTC, HH and UVA-55 cohorts.

		Univariate			Multivariablea
Cohort	Gene symbol	Hazard ratio	95% CI	p-value	Hazard ratio	95% CI	p-value
TTC	ALG5 (218203_at)	2.42	1.57–3.75	p < 0.0001	1.90	1.10–3.29	0.0209
	GPR107 (211979_at)	0.337	0.199–0.574	p < 0.0001	0.361	0.190–0.686	0.00185
	NUP188 (212691_at)	0.340	0.199–0.581	p < 0.0001	0.260	0.126–0.536	0.000263
HH	ALG5	1.60	1.03–2.49	0.0368	1.62	1.06–2.49	0.0255
	GPR107	0.948	0.343–2.63	0.92	0.801	0.273–2.36	0.687
	NUP188	0.984	0.671–1.44	0.935	0.953	0.647–1.41	0.810
UVA-55	ALG5 (218203_at)	3.08	1.07–8.81	0.0365	3.36	1.05–10.7	0.0406
	GPR107 (211979_at)	0.451	0.117–1.75	0.249	0.447	0.113–1.77	0.252
	NUP188 (212691_at)	0.398	0.11–1.44	0.160	0.289	0.0616–1.36	0.116

Bold values indicate statistical significance p < 0.05.

^aMultivariable analysis adjusted for stage and age. Gene expression, stage and age as continuous variables.