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. 2021 Mar 25;14:1085–1110. doi: 10.2147/JIR.S294630

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© 2021 Wang et al.

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Relative abundance of different diversity between different groups in colon (phylogenetic diversity index). (A–D) The genera with significant differences at the genus level in the different groups (MetaStat). (E) Phylogenetic tree of the linear discriminant analysis (LDA) scores for differentially abundant genera. y-WKY (blue), y-WKY-S (purple), y-SHR (red) and y-SHR-S (green) (LefSe). (F) The relative proportion of Bifidobacterium between different groups. (G) The relative proportions of lactate-producing bacteria in the gut microbiota in difference groups. Sequence reads were classified according to the primary end product of the assigned bacterial genera. Genera were classified into more than one group correspondingly if they were defined as producers of multiple metabolites. Results were compared by Unpaired t-test; *p < 0.05, **p < 0.01, ***p < 0.001 (Black y-SHR-S vs y-WKY, Blue y-WKY-S vs y-WKY, Green y-SHR vs y-WKY); ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 (y-SHR-S vs y-SHR); ^Δp < 0.05, ^ΔΔp < 0.01, ^ΔΔΔp < 0.001 (Black y-SHR-S vs y-WKY-S, Green y-SHR vs y-WKY-S).