Figure 3.

Heatmap and sample clustering. Z-score abundance heatmap with hierarchical Ward’s D2 linkage clustering based on Jaccard distances. The heatmap was created as a subset of features (74 out of 1004) with abundances above 800 reads. Colour codes were added to identify samples according to disease/treatment conditions, hierarchical cluster, and Dirichlet multinomial mixture (DMM) groups as defined in Fig. 2B.