Table 2.
Differential testing of microbial relative abundance.
| Filifactor | Parvimonas | Porphyromonas | |
|---|---|---|---|
| Median (IQR) | |||
| Controls | 0.12 (0.05–0.25) | 0.38 (0.12–1.02) | 3.0 (2.0–5.1) |
| EoE baseline | 0 (0–0.13) | 0.11 (0–0.22) | 1.3 (0.6–3.0) |
| EoE post-treatment | 0 (0–0.11) | 0.22 (0–0.38) | 0.9 (0.2–2.5) |
| Subjects with % > 0 | 31 (47.7%) | 45 (69.2%) | 60 (92.3%) |
| BH-adjusted p-values (FDR) | |||
| Controls vs. EoE baseline | 0.090 | 0.003 | 0.047 |
| Controls vs. post-Tx | 0.025 | 0.042 | 0.006 |
Median and interquartile range (IQR) of each group for the three genera that showed significant differences and percentage of subjects (out of 65) in which each genus was detected. Output adjusted p-values (Benjamini–Hochberg correction) of the statistical comparisons are also provided. EoE: eosinophilic oesophagitis; post-Tx: EoE patients after treatment; BH: Benjamini–Hochberg correction; FDR: false discovery rate.