Table 3.
Prognostic factors related to patients’ mortality.
| Univariate analysis | Multivariable analysis | |||
|---|---|---|---|---|
| HR [95% CI] | p value | HR [95% CI] | p value | |
| Age | 1.08 [1.07, 1.09] | < 0.001 | 1.07 [1.06, 1.09] | < 0.001 |
| Sex (female) | 1.28 [1.09, 1.51] | 0.003 | 0.85 [0.68, 1.06] | 0.137 |
| Diabetes mellitus | 1.75 [1.49, 2.05] | < 0.001 | 1.52 [1.22, 1.88] | < 0.001 |
| Hypertension | 1.27 [1.09, 1.49] | 0.002 | 0.88 [0.72, 1.08] | 0. 228 |
| Current smoker | 0.77 [0.65, 0.92] | 0.003 | 1.27 [1.00, 1.60] | 0.047 |
| Systolic BP | 1.00 [0.99, 1.00] | 0.367 | – | – |
| Diastolic BP | 1.00 [0.99, 1.00] | 0.076 | – | – |
| Body mass index | 0.85 [0.83, 0.88] | < 0.001 | 0.93 [0.90, 0.96] | < 0.001 |
| Hemoglobin | 0.73 [0.70, 0.76] | < 0.001 | 0.99 [0.93, 1.05] | 0.748 |
| RDW-CV | 1.24 [1.20, 1.28] | < 0.001 | 1.13 [1.07, 1.20] | < 0.001 |
| Ln (Total lymphocyte) | 0.39 [0.33, 0.46] | < 0.001 | – | – |
| Albumin | 0.25 [0.22, 0.28] | < 0.001 | – | – |
| eGFR | 0.97 [0.97, 0.97] | < 0.001 | 0.99 [0.99, 1.00] | 0.051 |
| Total bilirubin | 1.16 [1.06, 1.26] | 0.001 | – | – |
| Uric acid | 1.14 [1.10, 1.19] | < 0.001 | 1.05 [1.00, 1.11] | 0.069 |
| CRP | 1.11 [1.10, 1.13] | < 0.001 | 1.05 [1.02, 1.08] | 0.001 |
| Proteinuria | 3.31 [2.76, 3.96] | < 0.001 | 1.48 [1.15, 1.89] | 0.002 |
| PNI | 0.90 [0.89, 0.91] | < 0.001 | 0.98 [0.96, 0.99] | 0.003 |
| AKI | 4.54 [3.796, 5.49] | < 0.001 | 2.17 [1.66, 2.84] | < 0.001 |
| Statin at discharge | 0.68 [0.54, 0.86] | 0.001 | 0.79 [0.61, 1.03] | 0.084 |
| ARB/ACEI at discharge | 0.61 [0.50, 0.74] | < 0.001 | 0.65 [0.52, 0.82] | < 0.001 |
HR hazard ratio, CI confidence interval, BP blood pressure, RDW-CV red cell distribution width coefficient of variation, eGFR estimated glomerular filtration rate, CRP C-reactive protein, PNI prognostic nutritional index, AKI acute kidney injury, ARB angiotensin II receptor blocker, ACEI angiotensin converting enzyme inhibitor.