Table 3. Correlating serology with biopsy results in histology cohort in age and T1DM groups.
| Groups (n) | Sensitivity % (95% CI) | Specificity % (95% CI) | Accuracy % (95% CI) | |
|---|---|---|---|---|
| TTG IgA (583) | 94 (90–96) | 86 (82–90) | 90 (87–92) | |
| DGP IgA (208) | 65 (50–77) | 95 (90–98) | 88 (83–92) | |
| DGP IgG (209) | 90 (77–96) | 96 (91–98) | 94 (90–97) | |
| TTG IgA | ||||
| <4 yr (106) | 98 (87–100) | 88 (77–94) | 92 (84–96) | |
| ≥4 yr (477) | 93 (89–96) | 86 (81–90) | 90 (87–92) | |
| DGP IgA | ||||
| <4 yr (40) | 100 (48–100) | 94 (81–99) | 95 (83–99) | |
| ≥4 yr (168) | 60 (44–75) | 95 (90–98) | 86 (80–91) | |
| DGP IgG | ||||
| <4 yr (40) | 100 (48–100) | 94 (81–99) | 95 (83–99) | |
| ≥4 yr (169) | 88 (74–96) | 96 (91–99) | 94 (89–97) | |
| TTG IgA | ||||
| Non T1DM (504) | 93 (88–96) | 91 (86–94) | 91 (87–94) | |
| T1DM (79) | 100 (93–100) | 42 (23–63) | 81 (71–89) | |
T1DM: type 1 diabetes mellitus, CI: confidence interval, TTG: tissue transglutaminase, DGP: deamidated gliadin peptide.