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. 2021 Mar 16;9:645658. doi: 10.3389/fcell.2021.645658

FIGURE 4.

FIGURE 4

Galectin-14 promotes trophoblast migration and invasion. (A) Primary extravillous trophoblasts (EVTs) were transfected with scramble siRNA or siRNA targeting galectin-14. (B) HTR-8/Svneo was transfected with empty vehicle or vector containing galectin-14 gene. (C) The galectin-14-overexpressed HTR/SVneo was transfected with scramble siRNA or siRNA targeting galectin-14. (A–C) The migration and invasion ability of EVTs were examined using transwell migration and invasion assays. Results are represented as mean ± SEM of biological triplicates. Statistical analysis: Student’s t-test. *p < 0.05, **p < 0.01, ***p < 0.001. Scale bar: 200 μm. si-Ctrl, cells transfected with scramble siRNA; gal-14-siRNA, cells transfected with siRNA targeting galectin-14; WT, HTR-8/SVneo transfected with empty vehicle; OE, galectin-14-overexpressed HTR-8/SVneo.