TABLE 1.

Acylation reactions at lysine residues of key regulatory proteins.

Acylation mechanism modification	Reaction	Donor Molecules	References
Two carbons modification	Acetylation	Acetyl-CoA	Huang et al., 2015; Xu J. Y. et al., 2018
Three carbons	Propionylation	Propionyl-CoA	Xu Y. et al., 2018
	Malonylation	Malonyl-CoA	Qian et al., 2016; Xu J. Y. et al., 2016
Four carbons	Butirylation	Butiryl-CoA	Xu J. Y. et al., 2018
	Succinylation	Succinyl-CoA	Weinert et al., 2013; Yang et al., 2015; Mizuno et al., 2016
	Crotonylation	Crotonyl-CoA	Xu et al., 2017
	β-Hydroxybutyrylation	β-Hydroxybutyryl-CoA	Xu J. Y. et al., 2018
	β-Isobutyrylation	β-Isobutyryl-CoA	Xu J. Y. et al., 2018
Five carbon	Glutarylation	Glutaryl-CoA	Hirschey and Zhao, 2015; Xie et al., 2016