Table 4.

Risk factors for in-hospital mortality

	Univariable analysis			Multivariable analysis
	OR	95% CI	P-Value	OR	95% CI	P-Value
Demographics
Age, years
<65	1 (Ref)
≥65	11.783	4.768—29.119	<0.001
Underlying diseases
Hypertension	8.806	3.156—20.716	<0.001
Diabetes	10.358	3.439—31.196	<0.001	10.474	1.554—70.617	0.016
Cardiovascular disease	15.818	3.964—63.118	<0.001
Clinical characteristics
Respiratory rate, breaths per min
≤24	1 (Ref)
>24	5.000	1.783—14.021	0.002
PSI score*	4.128	2.600—6.553	<0.001
SOFA score*	3.212	2.079—4.961	<0.001	3.077	1.848—5.122	<0.001
APACHEII score*	1.502	1.268—1.779	<0.001
Laboratory findings
White blood cell counts, × 109 per L
4—10	1 (Ref)
<4	0.081	0.026—0.248	<0.001
>10	0.056	0.014—0.231	<0.001
Lymphocyte counts, × 109 per L
≥0.8	1 (Ref)
<0.8	12.676	5.011—32.068	<0.001
Platelet counts, × 109 per L
≥100	1 (Ref)
<100	6.900	1.812—26.273	0.005
Total bilirubin, μmol/L
≤20	1 (Ref)
>20	8.359	3.321—21.042	<0.001
Albumin, g/L
≥35	1 (Ref)
<35	7.589	3.195—18.025	<0.001
Urea nitrogen, mmol/L
<11	1 (Ref)
≥11	18.413	4.672—72.560	<0.001
Creatinine, μmol/L
≤133	1 (Ref)
>133	11.250	2.068—61.213	0.005
Lactate dehydrogenase, U/L
≤245	1 (Ref)			13.169	2.934—59.105	0.001
>245	22.927	7.918—66.384	<0.001
D-dimer, μg/L
≤500	1 (Ref)
>500	9.107	3.700—22.417	<0.001

Abbreviations: PSI, Pneumonia Severity Index; SOFA, Sequential Organ Failure Assessment; APACHE||, Acute Physiology and Chronic Health Evaluation||.

^*Per 1 unit increase.