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. 2021 Mar 16;8:646808. doi: 10.3389/fmolb.2021.646808

TABLE 1.

Structures and tissue distribution of glycosaminoglycans.

Glycosaminoglycans Degree of sulfation per disaccharide unit Molecular weight range Tissue distribution
Heparin/Heparan sulfate (HS) graphic file with name fmolb-08-646808-i001.jpg Heparin about 1.8∼2.4 Heparin about 3∼30 kDa Heparin in liver, lungs and skin;
HS about 0.8∼1.8 HS about 10∼100 kDa HS was widely distributed on the cell surface.
Chondroitin sulfate (CS) graphic file with name fmolb-08-646808-i002.jpg 0.1–1.3 5∼50 kDa cartilage, tendon, aorta, ligament
Dermatan sulfate (DS) graphic file with name fmolb-08-646808-i003.jpg < 1 15∼40 kDa skin, blood vessels, heart valves
Hyaluronic acid (HA) graphic file with name fmolb-08-646808-i004.jpg 0 4∼12000 kDa synovial fluid, vitreous humour, ECM of loose connective tissue
Keratan sulfate (KS) graphic file with name fmolb-08-646808-i005.jpg < 1 5∼25 kDa KS I in cornea; KS II in cartilage aggregated; KS III in brain tissue