TABLE 1.
Glycosaminoglycans | Degree of sulfation per disaccharide unit | Molecular weight range | Tissue distribution | |
Heparin/Heparan sulfate (HS) | Heparin about 1.8∼2.4 | Heparin about 3∼30 kDa | Heparin in liver, lungs and skin; | |
HS about 0.8∼1.8 | HS about 10∼100 kDa | HS was widely distributed on the cell surface. | ||
Chondroitin sulfate (CS) | 0.1–1.3 | 5∼50 kDa | cartilage, tendon, aorta, ligament | |
Dermatan sulfate (DS) | < 1 | 15∼40 kDa | skin, blood vessels, heart valves | |
Hyaluronic acid (HA) | 0 | 4∼12000 kDa | synovial fluid, vitreous humour, ECM of loose connective tissue | |
Keratan sulfate (KS) | < 1 | 5∼25 kDa | KS I in cornea; KS II in cartilage aggregated; KS III in brain tissue |