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. 2021 Mar 16;11:637018. doi: 10.3389/fcimb.2021.637018

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Copyright © 2021 Chen, Cheng, Cai, Wei, Li, Liang, Zhang, Yu, Liu, Liu, Zhang, Wang and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of pleural effusion microbiome composition among the HA- and LA-SA types. (A) Venn diagram showing the number of shared and unique species in the HA- and LA-SA group. (B) Heat map of the microbiome species composition for all samples. The abundance of each species was clustered to represent a heatmap. (C) Differentially abundant species were identified using linear discriminant analysis (LDA) coupled with effect size measurements (LEfSe). The cutoff value of the linear LDA was ≥3.5.