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Predicted effects on the pathways of ganglioside biosynthesis when individual enzyme activities are completely inhibited or knocked-out. Panels 1–10 correspond to the enzymes of Table 2. Enzyme reactions are shown as lines colored according to the type of sugar transferred: yellow (galactosyltransferases); blue (glucosyltransferases); brown (N-acetylgalactosaminyltransferases).
