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. 2021 Mar 16;11:576232. doi: 10.3389/fonc.2021.576232

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Copyright © 2021 Liang, Makamure, Shu, Zhang, Sun and Zheng

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Funnel plot for the publication bias test of included studies with regard to CR at M1 (A), ORR at M1 (B), DCR at M1 (C), CR at M3 (D), ORR at M3 (E), DCR at M3 (F), CR at M6 (G), ORR at M6 (H), DCR at M6 (I), PFS (J), OS (K), pain post operation (L), fever post operation (M), nausea/vomiting post operation (N), ALT at M1 (O), AST at M1 (P) and TB at M1 (Q). CR, complete response; ORR, objective response rate; DCR, disease control rate; M1, 1 month; M3, 3 months; M6, 6 months; ALT, alanine aminotransferase; AST, aspartate aminotransferase; TB, total bilirubin.