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. 2021 Mar 16;11:614172. doi: 10.3389/fonc.2021.614172

Table 5.

Performance of model versus radiologists of clinical experience <5 years, 5–10 years, and >10 years in diagnosing malignant nodules on the test set and its subsets.

Diagnostic method AUC Accuracy Sensitivity Specificity Precision
Test set Model 0.924 0.851 0.881 0.839 0.673
Radiologist <5 yr 0.818 0.868 0.707 0.928 0.784
Radiologist 5–10 yr 0.843 0.864 0.798 0.888 0.726
Radiologist >10 yr 0.848 0.858 0.826 0.87 0.701
P-Value* <0.01 0.781 <0.01 <0.01 0.016
P-Value** <0.01 1.000 0.001 0.04 0.346
P-Value*** <0.01 0.733 0.777 0.3 0.752
HT subset Model 0.924 0.852 0.881 0.846 0.540
Radiologist <5 yr 0.824 0.897 0.723 0.924 0.588
Radiologist 5–10 yr 0.857 0.875 0.831 0.882 0.514
Radiologist >10 yr 0.863 0.863 0.862 0.863 0.487
P-Value* <0.01 0.401 0.001 0.003 0.226
P-Value** <0.01 0.928 0.060 0.312 0.811
P-Value*** <0.01 0.787 0.486 1.000 0.874
Normal subset Model 0.906 0.843 0.871 0.822 0.784
Radiologist <5 yr 0.825 0.842 0.712 0.938 0.893
Radiologist 5–10 yr 0.846 0.853 0.797 0.894 0.847
Radiologist >10 yr 0.844 0.85 0.804 0.885 0.837
P-Value* <0.01 0.603 0 0 0.017
P-Value** <0.01 0.916 0.01 0.035 0.179
P-Value*** <0.01 0.833 0.015 0.072 0.272

P-Value* is that of model versus radiologist with <5 years’ clinical experience; P-Value** is that of model versus radiologist with 5–10 years’ clinical experience; P-Value*** is that of model versus radiologist with >10 years’ clinical experience; AUC, Areas under the ROC curve.

All metrics were the average of 10-folds.