Table 1.

Characteristics of studies on the prevalence of positive thyroid antibodies in patients with pemphigus.

Study	Country	Thyroid function tests	Pemphigus patients (PV)			Controls			Positive anti-TPO, %			Positive anti-Tg, %			NOS Score
			n	Female/Male	Mean Age (years)	n	Female/Male	Mean Age (years)	Patients	Controls	p value	Patients	Controls	p value
Seiffert-Sinha et al. (15)	USA	Anti-Tg, Anti-TPO	225	148/77	52.9 ± 14.4	148	58/90	46.0 ± 18.7	13.9	7.2	0.042	6.8	0. 6	<0.001	7
Ameri et al. (16)	Italy	TSH, Anti-Tg, Anti-TPO	25	16/9	62.88 ± 16.54	46	20/26	63.26 ± 17.47	24	6.5	n.s.	12	2.2	n.s.	6
Kavala et al. (17)	Turkey	fT3, fT4, TSH, Anti-Tg, Anti-TPO	80	54/26	52.5	80	54/26	51.5	8	1.2	< 0.05	2.5	1.2	> 0.05	7
Daneshpazhooh et al. (18)	Iran	fT3, fT4, TSH, Anti-Tg, Anti-TPO	75	41/34	45.76 ± 1.79	65	28/37	41.13 ± 1.77	16	12.3	0.53	9.3	9.2	0.98	5
Ansar et al. (19)	Iran	T3, T4, TSH, Anti-TPO	22	14/8	35.04 ± 9.28	33	21/12	33.66 ± 9.13	22.7	6	< 0.05	n.a.	n.a.	n.a.	6
Pitoia et al. (20)	Argentina	T3, T4, TSH, Anti-TPO	15	9/6	48.3 ± 11.3	15	9/6	45.4 ± 12.2	40	6.7	n.a.	n.a.	n.a.	n.a.	7
Wang et al., the present study, 2021	China	Anti-Tg, Anti-TPO	66	36/30	51.65 ± 1.73	65	39/26	52.39 ± 0.75	16	6	0.034	20	12	0.1545

n, Number; PV, pemphigus vulgaris; TG, thyroglobulin; TPO, thyroid peroxidase; TSH, thyroid stimulating hormone; T3, triiodothyronine; T4, thyroxine; NOS, Newcastle-Ottawa scale.