Table 3.
Prevalence of abnormal low T cell subset counts in the peripheral blood of PV patients and PF patients.
| PV Patients | PF Patients | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| anti-TPO +(n=9) | anti-TPO –(n=49) | p^ | anti-Tg + (n=9) | anti-Tg - (n=49) | p^ | anti-TPO + (n=4) | anti-TPO - (n=30) | p^ | anti-Tg + (n=6) | anti-Tg - (n=28) | p^ | |
| n, % (CD3 count < 690 n/µl) |
0 (0) | 6 (12.24%) | 0.576 | 0 (0) | 6 (12.24%) | 0.576 | 0 (0) | 3 (10%) |
> 0.999 | 0 (0) | 3 (10%) |
> 0.999 |
| n, % (CD4 count< 410 n/µl) |
1 (11.11%) | 11 (22.45%) | 0.668 | 2 (22.22%) | 8 (16.32%) | 0.646 | 1 (25%) |
5 (16.67%) |
0.559 | 2 (33.33%) | 4 (14.29%) | 0.620 |
| n, % (CD8 count < 190 n/µl) |
1 (11.11%) | 7 (14.29%) |
> 0.999 | 0 | 8 (16.32%) | 0.334 | 1 (25%) |
3 (10%) |
0.431 | 1 (16.67%) | 3 (10.71%) | > 0.999 |
n, number; PV, pemphigus vulgaris; PF, pemphigus foliaceus; TG, thyroglobulin; TPO, thyroid peroxidase.
Normal counts for T cell subsets: CD3: 690-2540 n/µl; CD4:410-1590 n/µl; CD8:190-1140 n/µl; Values > 20 IU/ml for anti-Tg or anti-TPO were defined as antibody cut-off.
^The Fisher’s exact test.