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. 2021 Mar 16;11:650487. doi: 10.3389/fcimb.2021.650487

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Copyright © 2021 Yuan, Yu, Jin, Wang, Gao, Ding, Zhuo, Zhu, Gao, Zheng, Ying, Xu, Kong, Lu and Lv

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation analysis between IgG antibody levels and neutralization antibody titers. (A–C), Correlation analysis between neutralizing titers and RBD-, S1-, and N-specific IgG levels, respectively. Convalescent plasma collected from 57 COVID-19-recovered patients was used for SARS-CoV-2 pseudotype neutralization assay to test IC₅₀ and indirect ELISA to test OD450 values at a fixed dilution (1:100). (D), correlation analysis between authentic SARS-CoV-2 neutralizing antibody titers and anti-RBD IgG levels in convalescent plasma. Statistics analysis was performed by using Graphpad prism 8.4 software. IC₅₀, half-maximum inhibitory concentration.